Alkaloids from Tripterygium wilfordii Hook: Wilforgine and Wilfortrine1

Journal of the American Chemical Society
1952.0

Abstract

After wilforine and wilfordine had been isolated from the methanol-insoluble fraction there remained two main alkaloidal fractions. From these fractions two new alkaloids, designated “wilforgine” and “wilfortrine,” were isolated by partition chromatography employing ultraviolet absorbancy ratios. The purity of the alkaloids was established by countercurrent distribution. The compounds are insecticidally active ester alkaloids, which upon saponification yield 1 mole of 3-furoic acid, 5 moles of acetic acid and 2 moles of steam non-volatile acid per mole of compound. Ultraviolet and infrared absorption spectra of the alkaloids are given. © 1952, American Chemical Society. All rights reserved.

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