Seven alkaloids, one of them previously unreported, have been isolated from Rauwolfia heterophylla. They are reserpine, ajmalicine, rauwolscine, yohimbine, ajmaline, serpentine and heterophyllin. Heterophyllin, a new alkaloid with the empirical formula C22H26N2O4, appears to be related in structure to ajmalicine. © 1955, American Chemical Society. All rights reserved.