Two novel bisindole alkaloids have been isolated from Pandaca caducifolia (Mgf): ervafolidene (10) and epi-ervafolidene (11). Their structure has been established by spectral analysis (especially 13C nmr) and by comparison with the known alkaloid ervafolene (3), also isolated from the plant. Several unusual reactions of 3 are described, among which is a rearrangement pertaining to the pandoline moiety of the molecule. © 1982, American Chemical Society. All rights reserved.