Four new 1-β-hydroxy and 1-β-methoxy C19-diterpene alkaloids have been prepared: l-epi-l-O-methyldelphisine {7}, l-epi-l-0-methylneoline [10), l-epi- 14-acetyl-neoline [13], and l-epi-1,14-diacetylneoline [15], as well as the new compounds, 1-O-methyl-delphisine [8] and 14-acetyl-l-dehydroneoline [12]. The structures of these compounds were established on the basis of spectral data and correlation with compounds of established structure.1H- and13C-nmr data are reported for each compound. © 1989, American Chemical Society. All rights reserved.