The seeds of Picralima nitida collected in Ghana afforded a new indole alkaloid, picratidine [1], whose structure was deduced as N-methylpicraline through interpretation of spectral data. Five other alkaloids, akuammine, akuammmidine, akuammicine, akuammigine, and pseudoakuammigine, were also isolated. © 1990, American Chemical Society. All rights reserved.