Two new alkaloids, tubacetine [3] and tubasenecine [4], were isolated from the aerial parts of Haplophyllum tuberculatum (Rutaceae). Their identities were established from nmr data, including a study of the 2D INADEQUATE spectra of the monoterpene part of 3. In addition, the alkaloid 7-hydroxy-8-(3-methyl-2-butenyl)-4-methoxyfuro[2,3b]quinoline [5] has been identified in this source for the first time. © 1992, American Chemical Society. All rights reserved.