347. Ipecacuanha alkaloids. Part II. The structure of protoemetine and a partial synthesis of (–)-emetine

J. Chem. Soc.
2004.0

Abstract

Protoemetine, a new alkaloid from ipecacuanha root, is shown to have the structure (V; R = CHO) and its properties are described. A partial synthesis of (-)-emetine from protoemetine has been achieved, thus showing that the two alkaloids have the same stereochemistry. The biogenetic significance of protoemetine is discussed.

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