Echinosulfonic acid D: an ESI MS n evaluation of a new cytotoxic alkaloid from the New-Caledonian sponge Psammoclemma sp.

Natural Product Research
2005.0

Abstract

A new bromoindolesulfonic acid derivative, echinosulfonic acid D (1) was isolated from the New-Caledonian sponge Psammoclemma sp. in a minute quantity. The structure of the alkaloid was established by spectroscopic methods and, in particular, by ESI MSn experiments. Echinosulfonic acid D was cytotoxic to KB cells (IC50 2 microg/mL).

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