Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity

Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity A novel [5.2.1]bicyclic amine is a potent analgesic without µ opioid activity Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity 3-(1-Indolinyl)benzylamines: a new class of analgesic agents Synthesis and analgesic profile of conformationally constrained N-acylhydrazone analogues: Discovery of novel N-arylideneamino quinazolin-4(3H)-one compounds derived from natural safrole Discovery, structure–activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists Novel 3-(4-piperidinylthio)-1 H -indoles as potent nonopioid orally active central analgesics Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain