Activity of new penems against defined MRSA strains

Bioorganic & Medicinal Chemistry Letters
1993.0

Abstract

The activity of penems against methicillin-resistant Staphylococcus aureus (MRSA) was determined on strains representative of the four expression classes of resistance. Two families of compounds, characterized by a C2(hetero)aromatic moiety connected by an ether (CH₂O) or ester (CH₂OCO) link, displayed superior activity in vitro.

DOI： 10.1016/S0960-894X(01)80919-7

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