Studies on the novel anti-staphyloccal compound nematophin

Bioorganic & Medicinal Chemistry Letters
2000.0

Abstract

A number of analogues of the recently described compound nematophin were prepared and studied for antibacterial activity. The 2-phenyl derivative was found to exhibit exceptional activity against methicillin resistant Staphylococcus aureus (MRSA) whereas the isosteric benzimidazole analogue was much less active.

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