Preparation and biological evaluation of γ-fluoromethyl-α-methylene-γ-butyrolactone and γ-butyrolactam

Preparation and biological evaluation of γ-fluoromethyl-α-methylene-γ-butyrolactone and γ-butyrolactam Antitumor agents. 25. Synthesis and antitumor activity of uracil and thymine .alpha.-methylene-.gamma.-lactones and related derivatives Synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents New .alpha.-methylene .gamma.-lactone derivatives of substituted nucleic acid bases as potential anticancer agents Synthesis and cytotoxic evaluation of halogenated α-exo-methylene-lactones Cytotoxic michael-type amine adducts of α-methylene lactones alantolactone and isoalantolactone Preparation and biological evaluation of β-Trifluoromethyl-α,β-unsaturated carbonyl compounds New α-methylene-γ-butyrolactones with antimycobacterial properties Synthesis and cytotoxic activity of some novel polycyclic γ-butyrolactones Design, synthesis and in vitro evaluation against human cancer cells of 5-methyl-5-styryl-2,5-dihydrofuran-2-ones, a new series of goniothalamin analogues