Aromatic amino acid phosphoramidate di- and triesters of 3′-azido-3′-deoxythymidine (AZT) are non-toxic inhibitors of HIV-1 replication

Aromatic amino acid phosphoramidate di- and triesters of 3′-azido-3′-deoxythymidine (AZT) are non-toxic inhibitors of HIV-1 replication Amino Acid Phosphoramidate Monoesters of 3‘-Azido-3‘-deoxythymidine:  Relationship between Antiviral Potency and Intracellular Metabolism S-Acyl-2-Thioethyl Aryl Phosphotriester Derivatives of AZT:  Synthesis, Antiviral Activity, and Stability Study Synthesis, in Vitro Anti-Breast Cancer Activity, and Intracellular Decomposition of Amino Acid Methyl Ester and Alkyl Amide Phosphoramidate Monoesters of 3‘-Azido-3‘-deoxythymidine (AZT) S-Acyl-2-thioethyl Phosphoramidate Diester Derivatives as Mononucleotide Prodrugs Probing the Mechanism of Action and Decomposition of Amino Acid Phosphomonoester Amidates of Antiviral Nucleoside Prodrugs Aryl phosphate derivates of AZT inhibit HIV replication in cells where the nucleoside is poorly active S-Acyl-2-thioethyl Aryl Phosphotriester Derivatives as Mononucleotide Prodrugs Diaryl phosphate derivatives act as pro-drugs of AZT with reduced cytotoxicity compared to the parent nucleoside Aryl nucleoside H-phosphonates. Part 16: Synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters