Synthesis and biological evaluation of 4-alkoxy substituted trinems. Part I

Bioorganic & Medicinal Chemistry Letters
1996.0

Abstract

Synthesis of new 4-alkoxy substituted trinems 4, 5, 6, 7 and 8 together with their antibacterial profiles compared to imipenem and GV104326 (2) are described. The good antibacterial profile observed for derivatives 4-7 encouraged further exploration of these derivatives.

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