Synthesis and antibacterial, activity of 4-ureido trinems

Bioorganic & Medicinal Chemistry Letters
1996.0

Abstract

This article describes studies carried out on the synthesis and biological activity of 4-ureido trinems 1 obtained by the condensation of various isocyanates and the intermediate 6. Among others, 4- N-methyl-N'-alkyl ureido trinems showed a promising antimicrobial activity against Gram-negative bacteria.

DOI： 10.1016/S0960-894X(96)00515-X

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