The synthesis and biological evaluation of a novel series of indole PDE4 inhibitors I

The synthesis and biological evaluation of a novel series of indole PDE4 inhibitors I Orally active indole N-oxide PDE4 inhibitors Novel Cyclic Compounds as Potent Phosphodiesterase 4 Inhibitors Novel indolizine compounds as potent inhibitors of phosphodiesterase IV (PDE4): structure–activity relationship Synthesis, Structure−Activity Relationships, and Pharmacological Profile of 9-Amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-hi]indoles:  Discovery of Potent, Selective Phosphodiesterase Type 4 Inhibitors Synthesis and biological activities of 1-pyridylisoquinoline and 1-pyridyldihydroisoquinoline derivatives as PDE4 inhibitors Phthalazine PDE4 inhibitors. Part 2: The synthesis and biological evaluation of 6-methoxy-1,4-disubstituted derivatives Quaternary substituted PDE4 inhibitors I: The synthesis and in vitro evaluation of a novel series of oxindoles Discovery of micromolar PDE IV inhibitors that exhibit much reduced affinity for the [3H]rolipram binding site: 3-norbornyloxy-4-methoxyphenylmethylene oxindoles The synthesis and biological evaluation of a novel series of phthalazine PDE4 inhibitors I