Design of new inhibitors for cdc2 kinase based on a multiple pseudosubstrate structure

Design of new inhibitors for cdc2 kinase based on a multiple pseudosubstrate structure Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides 2-aryl-indolyl maleimides - novel and potent inhibitors of protein kinase C Structure-based design of a new class of highly selective aminoimidazo[1,2-a]pyridine-based inhibitors of cyclin dependent kinases Studies on cyclin-dependent kinase inhibitors: indolo-[2,3- a ]pyrrolo[3,4- c ]carbazoles versus bis-indolylmaleimides Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3 Design and synthesis of new leads for PKC bisubstrate inhibitors. Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCβ Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction