Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors

Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine−Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment of Alzheimer's Disease Discovery of Huperzine A−Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Midgorge Recognition Sites Synthesis and evaluation of tacrine–E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease New Tacrine−Huperzine A Hybrids (Huprines):  Highly Potent Tight-Binding Acetylcholinesterase Inhibitors of Interest for the Treatment of Alzheimer's Disease Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors Syntheses of coumarin–tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase Synthesis and acetylcholinesterase inhibitory activity of (±)-14-fluorohuperzine A Bis-huperzine B:  Highly Potent and Selective Acetylcholinesterase Inhibitors