BN 80927: A novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II
Bioorganic & Medicinal Chemistry Letters
1999.0
Abstract
BN 80927, a novel homocamptothecin derivative, inhibits both topoisomerase I and topoisomerase II mediated DNA relaxation and shows pronounced cytotoxicity against HT29, SKOV-3, DU145 and MCF7 human tumor cell lines.