Potent, orally absorbed glucagon receptor antagonists

Potent, orally absorbed glucagon receptor antagonists Discovery of a Novel Glucagon Receptor AntagonistN-[(4-{(1S)-1-[3-(3, 5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the Treatment of Type II Diabetes BI-32169, a Bicyclic 19-Peptide with Strong Glucagon Receptor Antagonist Activity from Streptomyces sp. Pyrroles and other heterocycles as inhibitors of P38 kinase BI-32169, a Bicyclic 19-Peptide with Strong Glucagon Receptor Antagonist Activity from <i>Streptomyces</i> sp. 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity Substituted 3-Imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino- [6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as Highly Selective and Potent Inhibitors of Glycogen Synthase Kinase-3 Discovery of Substituted Maleimides as Liver X Receptor Agonists and Determination of a Ligand-Bound Crystal Structure Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A 4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists