Isotope edited NMR studies of glycosidases: design and synthesis of a novel glycosidase inhibitor

Bioorganic & Medicinal Chemistry Letters
1999.0

Abstract

N-13C-methyl-deoxynojirimycin was synthesized and used in isotope-edited NMR studies to probe the binding site of an alpha-glucosidase. Results from this analysis led to the design and preparation of a novel alpha-glucosidase inhibitor, N-glycyl deoxynojirimycin.

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