Synthesis of polyamine derivatives Having non-hypotensive Ca2+-permeable AMPA receptor antagonist activity
Bioorganic & Medicinal Chemistry Letters
2001.0
Abstract
In order to obtain non-hypotensive and Ca2+-permeable AMPA receptor antagonists, we have synthesized a series of 1,4-bis(4-piperidinylmethyl)diaminobutanes. Compounds 13b, c, f had desirable properties.