The 5-HT 3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist

The 5-HT 3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist Activity of α7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes N-(quinuclidin-3-YL)-1,8,-naphthalimides with 5-HT3 receptor antagonist and 5-HT4 receptor agonist properties Design and synthesis of novel ligands for the 5-HT3 and the 5-HT4 receptor High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide: a high affinity 5-HT3 receptor partial agonist 2-(Arylmethyl)-3-substituted quinuclidines as selective α7 nicotinic receptor ligands Novel, Potent, and Selective Quinoxaline-Based 5-HT₃Receptor Ligands. 1. Further Structure−Activity Relationships and Pharmacological Characterization Zatosetron, a potent, selective, and long-acting 5HT3 receptor antagonist: synthesis and structure-activity relationships Synthesis, biological in vitro evaluation and stereoselectivity of ondansetron analogues: novel 5-HT2A receptor antagonists