Aminoglycoside antibiotics, neamine and its derivatives as potent inhibitors for the RNA–protein interactions derived from HIV-1 activators

Aminoglycoside antibiotics, neamine and its derivatives as potent inhibitors for the RNA–protein interactions derived from HIV-1 activators Neamine dimers targeting the HIV-1 TAR RNA Evaluation of neomycin analogues for HIV-1 RRE RNA recognition identifies enhanced activity simplified neamine analogues Synthesis and evaluation of novel neamine derivatives effectively targeting to RNA Nucleobase modified neamines with a lysine as a linker, their inhibition specificity for TAR-Tat derived from HIV-1 A Peptide Nucleic Acid−Neamine Conjugate That Targets and Cleaves HIV-1 TAR RNA Inhibits Viral Replication Inhibition of an HIV-1 Tat-derived peptide binding to TAR RNA by aminoglycoside antibiotics Studies on the synthesis of neamine-dinucleosides and neamine-PNA conjugates and their interaction with RNA Study of aminoglycoside–nucleic acid interactions by an HPLC method Binding of dimeric aminoglycosides to the HIV-1 rev responsive element (RRE) RNA construct