Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus

Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles HIV-1 protease inhibitors with picomolar potency against PI-resistant HIV-1 by modification of the P1′ substituent P1′ oxadiazole protease inhibitors with excellent activity against native and protease inhibitor-resistant HIV-1 Novel inhibitors of HIV protease Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains The design, synthesis and evaluation of novel HIV-1 protease inhibitors with high potency against PI-resistant viral strains