Synthesis of novel fluorescent probes for the molecular chaperone Hsp90

Synthesis of novel fluorescent probes for the molecular chaperone Hsp90 Synthesis of a red-shifted fluorescence polarization probe for Hsp90 Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Heat Shock Protein 90 A small molecule that preferentially binds the closed conformation of Hsp90 Synthesis of Hsp90 dimerization modulators Discovery and development of heat shock protein 90 inhibitors Virtual screening and biophysical studies lead to HSP90 inhibitors From Bacteria to Cancer: A Benzothiazole-Based DNA Gyrase B Inhibitor Redesigned for Hsp90 C-Terminal Inhibition Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions