Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis

Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors Unique Overlap in the Prerequisites for Thrombin Inhibition and Oral Bioavailability Resulting in Potent Oral Antithrombotics Design, synthesis, and evaluation of orally active fibrinogen inhibitors From natural products to achiral drug prototypes: Potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs Structure-Based Approach for the Discovery of Bis-benzamidines as Novel Inhibitors of Matriptase Structure-based optimization of non-peptidic Cathepsin D inhibitors Structure–activity relationship of 2,4,5-trioxoimidazolidines as inhibitors of thymidine phosphorylase Design, synthesis, and structure–activity relationship studies of new phenolic DNA gyrase inhibitors