Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site

Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor The Serotonin 5-HT4 Receptor. 1. Design of a New Class of Agonists and Receptor Map of the Agonist Recognition Site Novel Potent and Selective Central 5-HT₃ Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT₃ Receptor Binding Site by Arylpiperazine Derivatives Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies Optimization of the Pharmacophore Model for 5-HT₇R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide: a high affinity 5-HT3 receptor partial agonist First pharmacophoric hypothesis for 5-HT 7 antagonism Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists Characterization of the 5-HT₇Receptor. Determination of the Pharmacophore for 5-HT₇Receptor Agonism and CoMFA-Based Modeling of the Agonist Binding Site