Isoform-Selective Substrates of Nitric Oxide Synthase

Isoform-Selective Substrates of Nitric Oxide Synthase N-Aryl N‘-Hydroxyguanidines, A New Class of NO-Donors after Selective Oxidation by Nitric Oxide Synthases:  Structure−Activity Relationship Oxidation of N^ω-Hydroxyarginine Analogues by NO-Synthase: The Simple, Non Amino Acid N-Butyl N‘-Hydroxyguanidine Is Almost as Efficient an NO Precursor as N^ω-Hydroxyarginine Guanidine-substituted imidazoles as inhibitors of nitric oxide synthase 4,4-Difluorinated analogues of l-arginine and NG-hydroxy-l-arginine as mechanistic probes for nitric oxide synthase 3,4-Dihydro-1-isoquinolinamines: A novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase Examination of N -hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies