Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore

Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors Development of a New Class of Nonimidazole Histamine H₃ Receptor Ligands with Combined Inhibitory Histamine N-Methyltransferase Activity Benzylamine histamine H3 antagonists and serotonin reuptake inhibitors Piperidine variations in search for non-imidazole histamine H3 receptor ligands Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo–keto reductase 1C3 target affinity Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts Discovery of Quinazolines as Histamine H₄Receptor Inverse Agonists Using a Scaffold Hopping Approach