Benzylamine histamine H3 antagonists and serotonin reuptake inhibitors

Bioorganic & Medicinal Chemistry Letters
2007.0

Abstract

The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described.

Knowledge Graph

Similar Paper

Benzylamine histamine H3 antagonists and serotonin reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters 2007.0
Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters 2007.0
Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors
Bioorganic & Medicinal Chemistry Letters 2007.0
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters 2009.0
New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine
Bioorganic & Medicinal Chemistry Letters 1998.0
Development of a New Class of Nonimidazole Histamine H<sub>3</sub> Receptor Ligands with Combined Inhibitory Histamine N-Methyltransferase Activity
Journal of Medicinal Chemistry 2002.0
From histamine to imidazolylalkyl-sulfonamides: The design of a novel series of histamine H3-receptor antagonists
Bioorganic &amp; Medicinal Chemistry Letters 1999.0
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists
European Journal of Medicinal Chemistry 2009.0
Synthesis and 5-HT3 receptor agonist activity of arylureas derived from histamine.
Bioorganic &amp; Medicinal Chemistry Letters 1993.0
Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore
Bioorganic &amp; Medicinal Chemistry Letters 2007.0