Multiple N-Methylation by a Designed Approach Enhances Receptor Selectivity

Multiple N-Methylation by a Designed Approach Enhances Receptor Selectivity Going Out on a Limb: Delineating The Effects of β-Branching, N-Methylation, and Side Chain Size on the Passive Permeability, Solubility, and Flexibility of Sanguinamide A Analogues Improving oral bioavailability of cyclic peptides by N-methylation Topographically designed analogs of [cyclic] [D-Pen2,D-Pen5]enkephalin Nonpeptide αvβ3 antagonists. Part 2: constrained glycyl amides derived from the RGD tripeptide Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: Synthesis, binding affinity and intrinsic activity for MT1 and MT2 melatonin receptors Rational Improvement of the Affinity and Selectivity of Integrin Binding of Grafted Lasso Peptides Synthesis and activity profiles of novel cyclic opioid peptide monomers and dimers Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3 Systematic N-methylation of oxytocin: Impact on pharmacology and intramolecular hydrogen bonding network