Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP

Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP Novel nucleotide triphosphates as potent P2Y2 agonists Synthesis and Structure−Activity Relationships of Uracil Nucleotide Derivatives and Analogues as Agonists at Human P2Y₂, P2Y₄, and P2Y₆Receptors Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists Molecular Modeling of the Human P2Y₂ Receptor and Design of a Selective Agonist, 2‘-Amino-2‘-deoxy-2-thiouridine 5‘-Triphosphate Identification of hydrolytically stable and selective P2Y1 receptor agonists Structural Modifications of UMP, UDP, and UTP Leading to Subtype-Selective Agonists for P2Y₂, P2Y₄, and P2Y₆ Receptors UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety Synthesis and P2Y2 receptor agonist activities of uridine 5′-phosphonate analogues Synthesis and P2Y receptor activity of nucleoside 5′-phosphonate derivatives