Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines

Bioorganic & Medicinal Chemistry Letters
2007.0

Abstract

In continuation of our earlier work on benzothiadiazines, we have prepared a series of nitrofuran, nitrothiophene and arylfuran coupled benzothiadiazines and evaluated them for antimycobacterial and antibacterial activities. One of the compounds 2f has shown good in vitro antimycobacterial activity. All the synthesized compounds have shown moderate to good antibacterial activity.

Knowledge Graph

Similar Paper

Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines
Bioorganic & Medicinal Chemistry Letters 2007.0
Heterocyclic benzazole derivatives with antimycobacterial In vitro activity
Bioorganic & Medicinal Chemistry Letters 2002.0
Identification of novel 2-aminothiazole conjugated nitrofuran as antitubercular and antibacterial agents
Bioorganic & Medicinal Chemistry Letters 2016.0
Synthesis and evaluation of antibacterial and antitubercular activities of some novel imidazo[2,1-b][1,3,4]thiadiazole derivatives
Medicinal Chemistry Research 2013.0
Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents
European Journal of Medicinal Chemistry 2010.0
Pyridine and nitro-phenyl linked 1,3,4-thiadiazoles as MDR-TB inhibitors
European Journal of Medicinal Chemistry 2019.0
Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents
Bioorganic & Medicinal Chemistry Letters 2007.0
Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents
European Journal of Medicinal Chemistry 2012.0
Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives
European Journal of Medicinal Chemistry 2015.0
Anti-tubercular agents. Part 5: Synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners
European Journal of Medicinal Chemistry 2010.0