Bioisosteric replacement of dihydropyrazole of 4S-(−)-3-(4-chlorophenyl)-N-methyl-N′-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole

Bioisosteric replacement of dihydropyrazole of 4S-(−)-3-(4-chlorophenyl)-N-methyl-N′-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide (SR141716) a potent CB1 receptor antagonist Biarylpyrazole Inverse Agonists at the Cannabinoid CB1 Receptor:  Importance of the C-3 Carboxamide Oxygen/Lysine3.28(192) Interaction Substituted 5,5‘-Diphenyl-2-thioxoimidazolidin-4-one as CB₁ Cannabinoid Receptor Ligands:  Synthesis and Pharmacological Evaluation Bioisosteric replacement of central 1,2,4-oxadiazole ring of high affinity CB₂ ligands by regioisomeric 1,3,4-oxadiazole ring Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists 1-Benzhydryl-3-phenylurea and 1-Benzhydryl-3-phenylthiourea Derivatives:  New Templates among the CB₁ Cannabinoid Receptor Inverse Agonists Tricyclic pyrazoles. Part 6. Benzofuro[3,2-c]pyrazole: A versatile architecture for CB2 selective ligands Bioisosteric prototype design of biaryl imidazolyl and triazolyl competitive histamine H2-receptor antagonists