Verbalactone, a New Macrocyclic Dimer Lactone from the Roots of Verbascum undulatum with Antibacterial Activity

Journal of Natural Products
2001.0

Abstract

A novel macrocyclic dimer lactone, named verbalactone, was isolated from the roots of Verbascum undulatum and exhibited interesting antibacterial activity. It is the first time that 1,7-dioxacyclododecane is reported as the ring system of a natural product. The structure and the absolute stereochemistry of the new compound were determined by spectral methods and chemical correlation.

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