Search for MDR modulators: Design, syntheses and evaluations of N-substituted acridones for interactions with p-glycoprotein and Mg2+

Search for MDR modulators: Design, syntheses and evaluations of N-substituted acridones for interactions with p-glycoprotein and Mg2+ Targeting efflux pumps—In vitro investigations with acridone derivatives and identification of a lead molecule for MDR modulation Acridones circumvent P-glycoprotein-associated multidrug resistance (MDR) in cancer cells Acridone derivatives: Design, synthesis, and inhibition of breast cancer resistance protein ABCG2 Discovery of pyridine-2-ones as novel class of multidrug resistance (MDR) modulators: First structure–activity relationships Design, synthesis, biological evaluation, molecular docking and QSAR studies of 2,4-dimethylacridones as anticancer agents Synthesis and antitumor activity of novel amsacrine analogs: The critical role of the acridine moiety in determining their biological activity Synthesis and Activity against Multidrug Resistance in Chinese Hamster Ovary Cells of New Acridone-4-carboxamides Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR) Design, synthesis and evaluations of acridone derivatives using Candida albicans—Search for MDR modulators led to the identification of an anti-candidiasis agent