Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists

Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds Discovery and Optimization of a Novel Series ofN-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB₂) Agonists Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors New class of potent ligands for the human peripheral cannabinoid receptor Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties