Discovery of novel potent and selective ligands for 5-HT2A receptor with quinazoline scaffold

Discovery of novel potent and selective ligands for 5-HT2A receptor with quinazoline scaffold Novel Potent and Selective Central 5-HT₃ Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT₃ Receptor Binding Site by Arylpiperazine Derivatives Novel quinazolinone derivatives as 5-HT7 receptor ligands Identification of tris-(phenylalkyl)amines as new selective h5-HT_2B receptor antagonists Synthesis and Pharmacological Characterization of a Series of Geometrically Constrained 5-HT_2A/2C Receptor Ligands Synthesis and 5-hydroxytryptamine antagonist activity of 2-[[2-(dimethylamino)ethyl]thio]-3-phenylquinoline and its analogs Synthesis, Potency, and in Vivo Evaluation of 2-Piperazin-1-ylquinoline Analogues as Dual Serotonin Reuptake Inhibitors and Serotonin 5-HT_1AReceptor Antagonists New 5-HT1A, 5HT2A and 5HT2C receptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR Design of a potent 5-HT4 receptor agonist with nanomolar affinity