Design and synthesis of peptide-based macrocyclic cyclophilin inhibitors

Design and synthesis of peptide-based macrocyclic cyclophilin inhibitors Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A Discovering Potent Small Molecule Inhibitors of Cyclophilin A Using de Novo Drug Design Approach Discovery of a potent peptidic cyclophilin A inhibitor Trp-Gly-Pro Synthesis of a tricyclic hexapeptide –via two consecutive ruthenium-catalyzed macrocyclization steps– with a constrained topology to mimic vancomycin's binding properties toward D-Ala-D-Ala dipeptide Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities Permeability of Cyclic Peptide Macrocycles and Cyclotides and Their Potential as Therapeutics Structure-activity studies of synthetic FKBP ligands as peptidyl-prolyl isomerase inhibitors Structure−Activity Studies of Ground- and Transition-State Analogue Inhibitors of Cyclophilin