A calcineurin antifungal strategy with analogs of FK506

A calcineurin antifungal strategy with analogs of FK506 Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity Calcineurin Inhibition or Mutation Enhances Cell Wall Inhibitors against Aspergillus fumigatus Targeting the Calcineurin Pathway Enhances Ergosterol Biosynthesis Inhibitors against Trichophyton mentagrophytes In Vitro and in a Human Skin Infection Model Preparation and in vitro activity of aryl ether derivatives of the FK-506 related immunosuppressive macrolides ascomycin and L-683,742 Chemical and Biological Characterization of Two FK506 Analogs Produced by Targeted Gene Disruption in Streptomyces sp. MA6548. One-step Heck Reaction Generates Nonimmunosuppressive FK506 Analogs for Pharmacological BMP Activation Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans Novel derivatives at the C21 position of the FK-506 macrocycle Antascomicins A, B, C, D and E. Novel FKBP12 Binding Compounds from a Micromonospora Strain.