Alkaloids fromHymenocallis littoralis

Chemistry of Natural Compounds
1982.0

Abstract

We determined the alkaloid content of leaves, roots, and bulbs of Crinum amabile Donn and first isolated lycorine, hippeastrine, crinidine, galanthine, galanthamine, narvedine, and tazettine from its bulb combined bases. We investigated previously unstudied Hymenocallis littoralis Salisb. from the Upper Volta and Ivory Coast, extracting total alkaloids from epigeal parts (0.25 ± 0.11%) and bulbs with roots (0.37 ± 0.13%). Via chromatography and acetone treatment, we isolated lycorine, trisphaerine, tazettine, hippeastrine, pancratine (hemanthidine), galanthamine, and amorphous bases (I, II); this is the first study of this species from these regions, yielding 8 bases including new trisphaeridine, hippeastrine, pancratine, galanthamine, and bases I, II besides known lycorine and tazettine. For Aconitum saposhnikovii from the Dolon Pass (Kirghiz SSR), we obtained 0.54% total alkaloids via chloroform extraction and isolated talatisamine, isoboldine, 14-acetyltalatisamine, and a new base 14-dehydrotalatisamine (identified by oxidizing talatisamine and comparing mixed melting point, IR spectra, and TLC). For Aconitum karacolicum from the upper R. Tyup (Kirghiz SSR) in the seed-ripening period, besides aconitine, songorine, isoboldine, and napelline N-oxide, we isolated a new base C24H35NO5 (mp 235°C, soluble in water/methanol, moderately in chloroform).

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