Secoiridoid glucosides from Fraxinus oxycarba

Phytochemistry
1998.0

Abstract

Three secoiridoid glucosides, fraxicarboside A, 6"-O-trans-p-coumaroyl-lO-hydroxyoleuropein, fraxicarboside B, 6"-O-trans-caffeoyl-lO-hydroxyoleuropein, and fraxicarboside C, 3"-O-acetyl-6"-O-transcaffeoyl-10-hydroxyoleuropein have been isolated for the first time from the leaves of Fraxinus oxycarba Willd. together with four known secoiridoids; oleuropein, ligstroside, 10-hydroxyoleuropein and 10-hydroxyligstroside, three known lignans; (+)-pinoresenol-4'-O-fi-o-glucopyranoside (+)-fraxiresinol-l-O-[/-oglucopyranoside and (+)-l-hydroxypinoresinol-4'-O-/~-D-glucopyranoside, two known phenylpropanoid glycosides; verbascoside (= acteoside), and 6-O-caffeoyl-/~-D-glucopyranoside, and three known flavonol glycosides; kaempferol-3-O-/3-o-glucopyranoside, kaempferol-3-O-~-L-rhamnopyranosyl-(l ~ 6)-fl-D-glucopyranoside and quercetin-3-O-~-L-rhamnopyranosyl-(1 ~ 6)-fl-D-glucopyranoside. The complete ~H and ~3C NMR spectral assignments of the new compounds were confirmed by the conventional 1D NMR methods and 2D shift-correlated techniques: COSY, HMBC and HMQC. :i(3 1998 Elsevier Science Ltd. All rights reserved

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