<jats:title>Abstract</jats:title><jats:p>Two new alkaloids, sessilifolines A (<jats:bold>1</jats:bold>) and B (<jats:bold>2a</jats:bold>), were isolated from the stems of <jats:italic>Stemona sessilifolia</jats:italic>, together with three known alkaloids, tuberstemonine (<jats:bold>3</jats:bold>), sessilifoliamide A (<jats:bold>4</jats:bold>), and stemoninoamide (<jats:bold>5</jats:bold>). Their structures were established by mass‐spectrometric and spectroscopic methods, especially 2D‐NMR techniques.