Two new alkaloids, sessilifoliamine A and sessilifoliamide J, having novel alkaloid skeletons were isolated from the roots of Stemona sessilifolia (Miq.) Miq. (Stemonaceae). The structure of sessilifoliamine A was determined by interpretation of its spectroscopic data and that of sessilifoliamide J by X-ray crystallography. © 2008 Elsevier Ltd. All rights reserved.