Chemical constituents of Aconitum barbatum var. puberulum

Chemistry of Natural Compounds
2009.0

Abstract

Aconitum barbatum var. puberulum is widely used in Chinese folk medicine for the treatment of rheumatosis, rheumatoid arthritis, and some other inflammations [1]. In our phytochemical investigation of traditional Chinese medicines, an aporphine alkaloid corydine (1) [2], a tricarboxylic unsaturated acid, aconitic acid (3) [3], and two diterpenoid alkaloids, tuguaconitine (2) [4] and luciculine (4) [5], were isolated and identified. These compounds were isolated from this plant for the first time. The 13C NMR of compound 1 was reported for the first time, and the 13C NMR of compounds 2 and 4 were reassigned.

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