Studies on the Constituents of Broussonetia Species. I. Two New Pyrrolidine Alkaloids, Broussonetines C and D, as .BETA.-Galactosidase and .BETA.-Mannosidase Inhibitors from Broussonetia kazinoki SIEB.

Chemical and Pharmaceutical Bulletin
1997.0

Abstract

Two new pyrrolidine alkaloids called broussonetines C and D were isolated from the branch of Broussonetia kazinoki SIEB. (Moraceae). Broussonetines C and D were formulated as (2R,3R,4R,5R)-2-hydroxymethyl-3,4dihydroxy-5-(10-oxo-13-hydroxytridecyl)pyrrolidine (1) and (2R,3R,4R,5R)-2-hydroxymethyl-3,4-dihydroxy-5-(9-oxo-13-hydroxytridecyl)pyrrolidine (2), respectively, by spectroscopic and chemical methods. 1 and 2 showed an inhibition to β-galactosidase and β-mannosidase.

DOI： 10.1248/CPB.45.505

Knowledge Graph

Similar Paper

Studies on the Constituents of Broussonetia Species. I. Two New Pyrrolidine Alkaloids, Broussonetines C and D, as .BETA.-Galactosidase and .BETA.-Mannosidase Inhibitors from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1997.0
Studies on the Constituents of Broussonetia Species. I. Two New Pyrrolidine Alkaloids, Broussonetines C and D, as .BETA.-Galactosidase and .BETA.-Mannosidase Inhibitors from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1997.0
Studies on the Constituents of Broussonetia Species. V. Two New Pyrrolidine Alkaloids, Broussonetines K and L, as Inhibitors of Glycosidase, from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1999.0
Studies on the Constituents of Broussonetia Species. V. Two New Pyrrolidine Alkaloids, Broussonetines K and L, as Inhibitors of Glycosidase, from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1999.0
Studies on the Constituents of Broussonetia Species. III. Two New Pyrrolidine Alkaloids, Broussonetia G and H, as Inhibitors of Glycosidase, from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1998.0
Studies on the Constituents of Broussonetia Species. VII. Four New Pyrrolidine Alkaloids, Broussonetines M, O, P, and Q, as Inhibitors of Glycosidase, from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 2000.0
Studies on the Constituents of Broussonetia Species. VII. Four New Pyrrolidine Alkaloids, Broussonetines M, O, P, and Q, as Inhibitors of Glycosidase, from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 2000.0
Studies on the Constituents of Broussonetia Species. II. Six New Pyrrolidine Alkaloids, Broussonetine A, B, E, F and Broussonetinine A and B, as Inhibitors of Glycosidases from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1997.0
Studies on the Constituents of Broussonetia Species. II. Six New Pyrrolidine Alkaloids, Broussonetine A, B, E, F and Broussonetinine A and B, as Inhibitors of Glycosidases from Broussonetia kazinoki SIEB.
Chemical and Pharmaceutical Bulletin 1997.0
A New Pyrrolizidine Alkaloid, Broussonetine N, as an Inhibitor of Glycosidase, from Broussonetia kazinoki SIEB. and Absolute Stereostructures of Broussonetines A and B.
Chemical and Pharmaceutical Bulletin 1999.0