A ‘one pot’ microwave-mediated synthesis of the basic canthine skeleton: expedient access to unnatural β-carboline alkaloids

Tetrahedron Letters
2003.0

Abstract

In a 'one pot' microwave reaction, an acyl hydrazide-tethered indole underwent a 3-component condensation to form a triazine, followed by an inverse-electron demand Diels-Alder reaction and subsequent chelotropic expulsion of N2 to deliver novel, unnatural β-carboline alkaloids in good isolated yields. © 2003 Elsevier Science Ltd. All rights reserved.

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