A new bishordeninyl terpene alkaloid, O-methylalfileramine [1], was isolated from the MeOH extract of the leaves of Zanthoxylum cbiriquinum, along with the already known alfileramine [2], culantraramine [3], and isoalfileramine [4]. This is the first report of the isolation of the two skeleton types of bishordeninyl terpene alkaloids from the same species. © 1990, American Chemical Society. All rights reserved.