Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups

Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups A bis-[N-3-(1-hydroxy-1-methyl-ethyl)-benzyl)-cyclic urea as a HIV protease inhibitor HIV Protease Inhibitory Bis-benzamide Cyclic Ureas:  A Quantitative Structure−Activity Relationship Analysis The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: Modifications of the P1/P1′ residues Cyclic HIV Protease Inhibitors:  Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323 Nonsymmetric P2/P2‘ Cyclic Urea HIV Protease Inhibitors. Structure−Activity Relationship, Bioavailability, and Resistance Profile of Monoindazole-Substituted P2 Analogues A Novel, Picomolar Inhibitor of Human Immunodeficiency Virus Type 1 Protease Preparation and Structure−Activity Relationship of Novel P1/P1‘-Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure